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Les protocoles ouverts

en gastro-entérologie

Innovations thérapeutiques :

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Projet SPECTA : L'objectif d'IMMUcan est de comprendre comment le système immunitaire et les tumeurs interagissent, et l'impact des interventions thérapeutiques.

Cohorte 1

  • Patients with a confirmed diagnostic of metastatic colorectal adenocarcinoma, with planned resection (curative intent) of the primary tumor and metastasis (liver and/or lung and/or peritoneal) in 1 or several successive surgical procedures and patients with metachronous metastatic disease are included as long as the resection specimen of the primary tumour is available (FFPE)

Cohorte 2

  • Patients with a diagnosis of widespread metastatic colorectal cancer not suitable for upfront surgery, with primary tumor tissue available from previous resection in early or palliative setting, with planned biopsy/resection of a metastatic lesion

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PEMBROLIZUMAB ASSOCIE AU XELOX BEVACIZUMAB CHEZ LES PATIENTS AVEC UN CANCER COLORECTAL METASTATIQUE MICROSATELLITE STABLE (MSS) ET UN FORT INFILTRAT IMMUNITAIRE : ETUDE PREUVE DE CONCEPT

Observatoires :

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